There was also the infamous book "The Lusty Argonian Maid" in Skyrim and the other Elder Scrollst games, about an imperial guy named Crantius Colto and his argonian (reptilian) maid "Lifs-Her-Tail" during an intense session of house cleaning.
Mass Effect was quite open to this things too, as there are a lot of references of interspecies sexuality. There was also an porn magazine mentioned, with special features about Krogans, a reptilian species with 4 testicles.
